Article
Lack of association between antipsychotic-induced extrapyramidal symptoms and polymorphisms in dopamine metabolism and transport genes.
Psychiatry research - 30 Jan 2010
Gassó Patricia, Mas Sergi, Crescenti Anna, Alvarez Santi, Parramon Gemma, Garcia-Rizo Clemente, Parellada Eduard, Bernardo Miquel, Lafuente Amalia
Abstract excerpt
The purpose of this study was to investigate the relationship between functional polymorphisms in genes coding for dopamine metabolism and transport enzymes and the incidence of acute antipsychotic (AP)-induced extrapyramidal symptoms (EPS). We did not find evidence of the involvement of these polymorphisms in the predisposition towards or protection from EPS.
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