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Article

Some dopaminergic genes polymorphisms are not associated with response to antipsychotic drugs in schizophrenic patients.

Pharmacological reports : PR - 1 Jan 2012

Tybura Piotr, Samochowiec Agnieszka, Beszlej Aleksander, Grzywacz Anna, Mak Monika, Frydecka Dorota, Bieńkowski Przemysław, Mierzejewski Paweł, Potemkowski Andrzej, Samochowiec Jerzy

Abstract excerpt

BACKGROUND: Therapeutic effects of all clinically used antipsychotics are related to the reduction of dopaminergic transmission in the limbic system. The aim of present study was two-fold. First, efficacy of atypical drugs (ziprasidone and olanzapine) against schizophrenia symptoms was compared to that offered by a typical antipsychotic medication, perazine. Second, associations between some dopaminergic genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22814006
DOI: 10.1016/s1734-1140(12)70848-4

Genes

DRD2
COMT
MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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