Article
Short allele of serotonin transporter gene promoter is a risk factor for obesity in adolescents.
Obesity (Silver Spring, Md.) - 1 Feb 2007
Sookoian Silvia, Gemma Carolina, García Silvia I, Gianotti Tomas Fernández, Dieuzeide Guillermo, Roussos Adriana, Tonietti Miriam, Trifone Liliana, Kanevsky Diego, González Claudio D, Pirola Carlos J
Abstract excerpt
Obesity and hypertension are increasing medical problems in adolescents. Serotonin transporter (5-HTT) is involved in mood and eating disturbances. Encoded by the gene SLC6A4, the promoter shows functional insertion/deletion alleles: long (L) and short (S). Because individuals who are carriers for the short version are known to be at risk for higher levels of anxiety, we hypothesized that this variant may be...
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