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Article

Hsp90 nuclear accumulation in quiescence is linked to chaperone function and spore development in yeast.

Molecular biology of the cell - 1 Jan 2010

Tapia Hugo, Morano Kevin A

Abstract excerpt

The 90-kDa heat-shock protein (Hsp90) operates in the context of a multichaperone complex to promote maturation of nuclear and cytoplasmic clients. We have discovered that Hsp90 and the cochaperone Sba1/p23 accumulate in the nucleus of quiescent Saccharomyces cerevisiae cells. Hsp90 nuclear accumulation was unaffected in sba1Delta cells, demonstrating that Hsp82 translocates independently of Sba1. Translocation...

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Identifiers

PMID: 19889838
DOI: 10.1091/mbc.e09-05-0376
PMCID: PMC2801720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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