Article
Investigation of Clade B New World Arenavirus Tropism by Using Chimeric GP1 Proteins
5 Nov 2009
Abstract excerpt
Clade B of the New World arenaviruses contains both pathogenic and nonpathogenic members, whose surface glycoproteins (GPs) are characterized by different abilities to use the human transferrin receptor type 1 (hTfR1) protein as a receptor. Using closely related pairs of pathogenic and nonpathogenic viruses, we investigated the determinants of the GP1 subunit that confer these different characteristics. We...
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