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Article

Association of telomere length with type 2 diabetes, oxidative stress and UCP2 gene variation.

Atherosclerosis - 1 Mar 2010

Salpea Klelia D, Talmud Philippa J, Cooper Jackie A, Maubaret Cecilia G, Stephens Jeffrey W, Abelak Kavin, Humphries Steve E

Abstract excerpt

OBJECTIVE: High oxidative stress potentially leads to accelerated telomere shortening and consequent premature cell senescence, implicated in type 2 diabetes (T2D) development. Therefore, we studied the association of leukocyte telomere length (LTL) with the presence of T2D, as well as the effect on the patients' LTL of plasma oxidative stress and of variation in UCP2, a gene involved in the mitochondrial...

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Source

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Identifiers

PMID: 19889414
DOI: 10.1016/j.atherosclerosis.2009.09.070
PMCID: PMC2839074

Genes

UCP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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