Article
The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM.
Gene - 15 Jan 2021
AlDehaini Dhuha M B, Al-Bustan Suzanne A, Malalla Zainab Hasan Abdulla, Ali Muhalab E, Sater Mai, Giha Hayder A
Abstract excerpt
Telomeres are duplex tandem repeats of DNA sequence 5'-TTAGGG-3' at chromosomal ends synthesized by telomerase enzyme (TE). Telomeres length (TL) shortening is associated with age and age-related disorders. Recently, we demonstrated marked leukocytes TL (LTL) shortening in T2DM. To set the relationship between the TE, LTL and T2DM, we analyzed samples from 212 Kuwaiti subjects, 112 patients withT2DM and 100...
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