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Article

Heat shock protein-derived T-cell epitopes contribute to autoimmune inflammation in pediatric Crohn's disease.

PloS one - 2 Nov 2009

Puga Yung Gisella L, Fidler Meredith, Albani Erika, Spermon Naomi, Teklenburg Gijs, Newbury Robert, Schechter Nicole, van den Broek Theo, Prakken Berent, Billetta Rosario, Dohil Ranjan, Albani Salvatore

Abstract excerpt

Pediatric Crohn's disease is a chronic auto inflammatory bowel disorder affecting children under the age of 17 years. A putative etiopathogenesis of Crohn's disease (CD) is associated with disregulation of immune response to antigens commonly present in the gut microenvironment. Heat shock proteins (HSP) have been identified as ubiquitous antigens with the ability to modulate inflammatory responses associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19888320
DOI: 10.1371/journal.pone.0007714
PMCID: PMC2765612

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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