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Article

REIC/Dkk-3 stable transfection reduces the malignant phenotype of mouse prostate cancer RM9 cells.

International journal of molecular medicine - 1 Dec 2009

Chen Jie, Watanabe Masami, Huang Peng, Sakaguchi Masakiyo, Ochiai Kazuhiko, Nasu Yasutomo, Ouchida Mamoru, Huh Nam-Ho, Shimizu Kenji, Kashiwakura Yuji, Kaku Haruki, Kumon Hiromi

Abstract excerpt

The reduced expression in immortalized cells (REIC)/Dickkopf (Dkk)-3, a member of the Dkk gene family, is a tumor suppressor in a broad range of cancers. REIC/Dkk-3 transfected stable clones of mouse prostate cancer RM9 cells (RM9-REIC) and the empty vector-transfected control clone cells (RM9-EV) were established. Clones were used to evaluate the anti-cancer effects and a proteomics analysis of REIC/Dkk-3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19885619
DOI: 10.3892/ijmm_00000293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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