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Article

Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-3

1 Jul 2007

Abstract excerpt

We recently showed that overexpression of REIC/Dickkopf-3 (Dkk-3), a tumor suppressor gene, induced apoptosis in a tumor cell-specific manner. The aim of the present study was to determine the mechanisms underlying the selective induction of apoptosis. At first, we found a mouse renal carcinoma cell line, RENCA, to be extremely sensitive to an adenovirus carrying REIC/Dkk-3 (Ad-REIC), and we showed that...

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Identifiers

PMID: 17549386
DOI: 10.3892/ijmm.20.1.37

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Source receipt: pubmed, retrieved 7 Sept 2026.

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