Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.

Genes & development - 1 Nov 2009

Munger Steven C, Aylor David L, Syed Haider Ali, Magwene Paul M, Threadgill David W, Capel Blanche

Abstract excerpt

Despite the identification of some key genes that regulate sex determination, most cases of disorders of sexual development remain unexplained. Evidence suggests that the sexual fate decision in the developing gonad depends on a complex network of interacting factors that converge on a critical threshold. To elucidate the transcriptional network underlying sex determination, we took the first expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breeding
Share to Cluster Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disorders of Sex Development

Share to Gonads

Share to Sex Determination Processes

Share to SOX9 Transcription Factor

Share to X Chromosome

Share to Y Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 19884258
DOI: 10.1101/gad.1835809
PMCID: PMC2779749

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.PMID 19884258Read ↗

Genetic Architecture of Sexual Dimorphism in HumansSemantic proximity Read ↗

Regulation of sex determination in mice by a non-coding genomic region.Semantic proximity Read ↗

Sex Differences in Early Embryogenesis: Inter‐Chromosomal Regulation Sets the Stage for Sex‐Biased Gene NetworksSemantic proximity Read ↗

Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammalsSemantic proximity Read ↗

Anomalies in human sex determination provide unique insights into the complex genetic interactions of early gonad development.Semantic proximity Read ↗

Strain-Dependent Functional Variation of a Sex Specific Sox9 Enhancer.Semantic proximity Read ↗

Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell typesSemantic proximity Read ↗

Identification of novel candidate genes for 46,XY disorders of sex development (DSD) using a C57BL/6J-Y POS mouse modelSemantic proximity Read ↗

Genetic factors contributing to extensive variability of sex-specific hepatic gene expression in Diversity Outbred mice.Semantic proximity Read ↗

Understanding the sexome: measuring and reporting sex differences in gene systems.Semantic proximity Read ↗

Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammalsSemantic proximity Read ↗

Sexually antagonistic epigenetic marks that canalize sexually dimorphic development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.