Article
Common genetic variants in pre-microRNAs are associated with risk of coal workers' pneumoconiosis.
Journal of human genetics - 1 Jan 2010
Wang Meilin, Ye Yang, Qian Haiyang, Song Zhifang, Jia Xiaomin, Zhang Zhengdong, Zhou Jianwei, Ni Chunhui
Abstract excerpt
microRNAs (miRNAs) are an abundant class of small noncoding RNA molecules thought to be involved in biological functions, including embryonic development, chromosome architecture, cell proliferation and apoptosis. We hypothesized that common variants in the miRNAs are associated with risk of coal workers' pneumoconiosis (CWP). In a case-control study of 496 CWP patients and 513 control subjects frequency matched...
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