Article
Life course variations in the associations between FTO and MC4R gene variants and body size.
Human molecular genetics - 1 Feb 2010
Hardy Rebecca, Wills Andrew K, Wong Andrew, Elks Cathy E, Wareham Nicholas J, Loos Ruth J F, Kuh Diana, Ong Ken K
Abstract excerpt
The timing of associations between common genetic variants for weight or body mass index (BMI) across the life course may provide insights into the aetiology of obesity. We genotyped variants in FTO (rs9939609) and near MC4R (rs17782313) in 1240 men and 1239 women born in 1946 and participating in the MRC National Survey of Health and Development. Birth weight was recorded and height and weight were measured or...
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