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Article

Increasing heritability of BMI and stronger associations with the FTO gene over childhood.

Obesity (Silver Spring, Md.) - 1 Dec 2008

Haworth Claire M A, Carnell Susan, Meaburn Emma L, Davis Oliver S P, Plomin Robert, Wardle Jane

Abstract excerpt

The growing evidence of health risks associated with the rise in childhood obesity adds to the urgency of understanding the determinants of BMI. Twin analyses on repeated assessments of BMI in a longitudinal sample of >7,000 children indicated that the genetic influence on BMI becomes progressively stronger, with heritability increasing from 0.48 at age 4 to 0.78 at age 11. In the same large twin sample, the...

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Source

Identifiers

PMID: 18846049
DOI: 10.1038/oby.2008.434

Genes

FTO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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