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Article

Influence of common variants in FTO and near INSIG2 and MC4R on growth curves for adiposity in African- and European-American youth.

European journal of epidemiology - 1 Jun 2011

Liu Gaifen, Zhu Haidong, Dong Yanbin, Podolsky Robert H, Treiber Frank A, Snieder Harold

Abstract excerpt

Recent genome-wide association (GWA) studies identified several common variants for obesity: rs9939609 in FTO, rs7566605 near INSIG2 and both rs17782313 and rs17700633 near the MC4R gene. This study aimed to assess the influence of these polymorphisms on development of adiposity in European- (EA) and African-American (AA) youth in two ongoing longitudinal studies including 986 and 606 participants with age ranges...

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Source

Open in PubMed Open full text

Identifiers

PMID: 21544599
DOI: 10.1007/s10654-011-9583-4
PMCID: PMC3115048

Genes

FTO
INSIG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of common variants in FTO and near INSIG2 and MC4R on growth curves for adiposity in African- and European-American youth.PMID 21544599Read ↗

Influence of common variants near INSIG2, in FTO, and near MC4R genes on overweight and the metabolic profile in adolescence: the TRAILS (TRacking Adolescents' Individual Lives Survey) Study.Semantic proximity Read ↗

BMI loci and longitudinal BMI from adolescence to young adulthood in an ethnically diverse cohort.Semantic proximity Read ↗

A common variant in the FTO locus is associated with waist-hip ratio in Indian adolescents.Semantic proximity Read ↗

Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.Semantic proximity Read ↗

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.Semantic proximity Read ↗

Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.Semantic proximity Read ↗

Common variants of FTO are associated with childhood obesity in a cross-sectional study of 3,126 urban Indian children.Semantic proximity Read ↗

EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in childrenSemantic proximity Read ↗

Prospective analysis of the association of a common variant of FTO (rs9939609) with adiposity in children: results of the IDEFICS study.Semantic proximity Read ↗

FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youthSemantic proximity Read ↗

Common variants near MC4R are associated with fat mass, weight and risk of obesity.Semantic proximity Read ↗

Association of FTO gene variants with adiposity in African-American adolescents.Semantic proximity Read ↗

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