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Article

Leucine-rich repeat transmembrane proteins instruct discrete dendrite targeting in an olfactory map.

Nature neuroscience - 1 Dec 2009

Hong Weizhe, Zhu Haitao, Potter Christopher J, Barsh Gabrielle, Kurusu Mitsuhiko, Zinn Kai, Luo Liqun

Abstract excerpt

Olfactory systems utilize discrete neural pathways to process and integrate odorant information. In Drosophila, axons of first-order olfactory receptor neurons (ORNs) and dendrites of second-order projection neurons (PNs) form class-specific synaptic connections at approximately 50 glomeruli. The mechanisms underlying PN dendrite targeting to distinct glomeruli in a three-dimensional discrete neural map are...

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Identifiers

PMID: 19915565
DOI: 10.1038/nn.2442
PMCID: PMC2826190

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