Article
Control of dendritic branching and tiling by the Tricornered-kinase/Furry signaling pathway in Drosophila sensory neurons.
Cell - 15 Oct 2004
Emoto Kazuo, He Ying, Ye Bing, Grueber Wesley B, Adler Paul N, Jan Lily Yeh, Jan Yuh-Nung
Abstract excerpt
To cover the receptive field completely but without redundancy, neurons of certain functional groups exhibit tiling of their dendrites via dendritic repulsion. Here we show that two evolutionarily conserved proteins, the Tricornered (Trc) kinase and Furry (Fry), are essential for tiling and branching control of Drosophila sensory neuron dendrites. Dendrites of fry and trc mutants display excessive terminal...
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