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Article

Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair.

Mutation research - 5 Jan 2010

Monti Paola, Traverso Ilaria, Casolari Laura, Menichini Paola, Inga Alberto, Ottaggio Laura, Russo Debora, Iyer Prema, Gold Barry, Fronza Gilberto

Abstract excerpt

We recently demonstrated that Polzeta and Rev1 contribute to alleviate the lethal effects of Me-lex, which selectively generates 3-methyladenine, by error prone lesion bypass. In order to determine the role of Poleta in the biological fate of Me-lex induced lesions, the RAD30 (Poleta) gene was deleted in the yIG397 parental strain and in its rev3 (Polzeta) derivative, and the strains transformed with plasmid DNA...

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Identifiers

PMID: 19874831
DOI: 10.1016/j.mrfmmm.2009.10.007
PMCID: PMC2794908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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