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Article

Sensitization of cervical carcinoma cells to paclitaxel by an IPP5 active mutant.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Zeng Qi-Yan, Huang Yu, Zeng Lin-Jie, Huang Min, Huang Yong-Qi, Zhu Qi-Fang

Abstract excerpt

Paclitaxel is one of the best anticancer agents that has been isolated from plants, but its major disadvantage is its dose-limiting toxicity. In this study, we obtained evidence that the active mutant IPP5 (8-60hIPP5m), the latest member of the inhibitory molecules for protein phosphatase 1, sensitizes human cervix carcinoma cells HeLa more efficiently to the therapeutic effects of paclitaxel. The combination of...

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Identifiers

PMID: 25339026
DOI: 10.7314/apjcp.2014.15.19.8337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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