Article
Role of uracil-DNA glycosylase in mutation avoidance by Streptococcus pneumoniae.
Journal of bacteriology - 1 Jan 1991
Chen J D, Lacks S A
Abstract excerpt
Uracil-DNA glycosylase activity was found in Streptococcus pneumoniae, and the enzyme was partially purified. An ung mutant lacking the activity was obtained by positive selection of cells transformed with a plasmid containing uracil in its DNA. The effects of the ung mutation on mutagenic proces...
Topics
- Base Composition
- Base Sequence
- DNA Glycosylases
- DNA Repair
- Escherichia coli
- Genotype
- Molecular Sequence Data
- Mutation
- N-Glycosyl Hydrolases
- Plasmids
- Streptococcus pneumoniae
- Thymidine
- Transformation, Bacterial
- Uracil
- Uracil-DNA Glycosidase