Article
Role of uracil-DNA glycosylase in mutation avoidance by Streptococcus pneumoniae.
Journal of bacteriology - 1 Jan 1991
Chen J D, Lacks S A
Abstract excerpt
Uracil-DNA glycosylase activity was found in Streptococcus pneumoniae, and the enzyme was partially purified. An ung mutant lacking the activity was obtained by positive selection of cells transformed with a plasmid containing uracil in its DNA. The effects of the ung mutation on mutagenic processes in S. pneumoniae were examined. The sequence of several malM mutations revertible by nitrous acid showed them to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
