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Article

Short-course Combivir after single-dose nevirapine reduces but does not eliminate the emergence of nevirapine resistance in women.

Antiviral therapy - 1 Jan 2012

Palmer Sarah, Boltz Valerie F, Chow Jeremy Y, Martinson Neil A, McIntyre James A, Gray Glenda E, Hopley Mark J, Mayers Douglas, Robinson Patrick, Hall David B, Maldarelli Frank, Coffin John M, Mellors John W

Abstract excerpt

BACKGROUND: In the Treatment Options Preservation Study (TOPS) trial, 4 or 7 days of Combivir (CBV; zidovudine/lamivudine) with maternal single-dose nevirapine (sdNVP) significantly reduced the emergence of NVP resistance as determined by virus population genotyping. To detect NVP resistance with...

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Identifiers

PMID: 22293443
DOI: 10.3851/IMP1946
PMCID: PMC6752704

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22293443-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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