Article
Intrapartum single-dose carbamazepine reduces nevirapine levels faster and may decrease resistance after a single dose of nevirapine for perinatal HIV prevention.
Journal of acquired immune deficiency syndromes (1999) - 1 Mar 2012
Muro Eva P, Fillekes Quirine, Kisanga Elton R, L'homme Rafaëlla, Aitken Susan C, Mariki Godfrey, Van der Ven Andre J A M, Dolmans Wil, Schuurman Rob, Walker A Sarah, Gibb Diana M, Burger David M
Abstract excerpt
BACKGROUND: World Health Organization guidelines recommend zidovudine + lamivudine for 7 days from labor onset in HIV-infected women receiving single-dose nevirapine (sdNVP) to cover prolonged subtherapeutic nevirapine concentrations. Although effective, this is complicated and does not eliminate resistance; alternative strategies could add benefit. METHODS: Antiretroviral-naive HIV-infected pregnant women aged...
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