Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence.

Antimicrobial agents and chemotherapy - 1 Jan 2010

Padilla Emma, Llobet Enrique, Doménech-Sánchez Antonio, Martínez-Martínez Luis, Bengoechea José Antonio, Albertí Sebastián

Abstract excerpt

Respiratory infections caused by Klebsiella pneumoniae are characterized by high rates of mortality and morbidity. Management of these infections is often difficult, due to the high frequency of strains that are resistant to multiple antimicrobial agents. Multidrug efflux pumps play a major role as a mechanism of antimicrobial resistance in Gram-negative pathogens. In the present study, we investigated the role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bronchoalveolar Lavage Fluid
Share to Defensins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Klebsiella Infections

Share to Klebsiella pneumoniae

Share to Mice, Inbred ICR

Share to Polymyxin B

Share to Polysaccharides

Share to RNA, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 19858254
DOI: 10.1128/AAC.00715-09
PMCID: PMC2798511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence.PMID 19858254Read ↗

Strain-dependent contribution of the AcrAB-TolC efflux pump to <i>Klebsiella pneumoniae</i> physiologySemantic proximity Read ↗

Efflux Pump AcrAB Confers Decreased Susceptibility to Piperacillin–Tazobactam and Ceftolozane–Tazobactam in Tigecycline-Non-Susceptible Klebsiella pneumoniaeSemantic proximity Read ↗

Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteriaSemantic proximity Read ↗

Overexpression of Efflux Pumps AcrAB and OqxAB Contributes to Ciprofloxacin Resistance in Clinical Isolates of K. pneumoniaeSemantic proximity Read ↗

The AcrAB-TolC efflux pump contributes to multidrug resistance in the nosocomial pathogen Enterobacter aerogenes.Semantic proximity Read ↗

AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants.Semantic proximity Read ↗

Overexpression of Efflux Pumps Mediate Pan Resistance of Klebsiella pneumoniae Sequence Type 11Semantic proximity Read ↗

Mutation-driven alterations in the AcrB efflux pump modulate antibiotic resistance in Klebsiella pneumoniae.Semantic proximity Read ↗

Mutations in the efflux regulator gene oqxR provide a simple genetic switch for antimicrobial resistance in Klebsiella pneumoniae.Semantic proximity Read ↗

AcrAB Efflux System: Expression and Contribution to Fluoroquinolone Resistance in Klebsiella sppSemantic proximity Read ↗

Moraxella catarrhalis AcrAB-OprM efflux pump contributes to antimicrobial resistance and is enhanced during cold shock response.Semantic proximity Read ↗

Expression of homologous RND efflux pump genes is dependent upon AcrB expression: implications for efflux and virulence inhibitor design.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.