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Overexpression of Efflux Pumps Mediate Pan Resistance of Klebsiella pneumoniae Sequence Type 11

9 Apr 2021

Abstract excerpt

A clinically isolated pan-resistant Klebsiella pneumoniae strain (ST11), KPN142 was subjected to whole-genome sequencing. Genomic sequence of KPN142 showed that limited antibiotic resistances (β-lactams [ bla shv-11 ], sulfonamides [ sul1 and dfrA22 ], bacitracin [ bacA ], tetracycline [ tet34 ], aminoglycosides [ ksgA , kdpE , aph(3)Ia , aac(3)III , and ant(3)Ia ], and chloramphenicol [ catA1 ]) were mediated by...

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PMID: 33835874
DOI: 10.1089/mdr.2020.0395

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