Article
[Influence of genetic factors on development and severity of rheumatoid arthritis--part I].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego - 1 Aug 2009
Trefler Jakub, Paradowska-Gorycka Agnieszka, Matyska-Piekarska Ewa, Rell-Bakalarska Maria, Wojciechowska Bozena, Łacki Jan K
Abstract excerpt
Both genetic and environmental factors affect susceptibility, severity and probably drugs' efficacy in patients with rheumatoid arthritis (RA). After initial completion of the Human Genome Project on the 16th February 2001, significant progress has been made in identifying other than HLA genome regions linked to the increased RA susceptibility. As an effect several new genes have been recognized as an...
Topics
- Antigens, CD
- Arthritis, Rheumatoid
- CTLA-4 Antigen
- DNA-Binding Proteins
- Genetic Predisposition to Disease
- Humans
- Interferon Regulatory Factors
- Organic Cation Transport Proteins
- Polymorphism, Genetic
- Protein Tyrosine Phosphatase, Non-Receptor Type 22
- Risk Factors
- STAT4 Transcription Factor