Article
OpuC--an ABC transporter that is associated with Staphylococcus aureus pathogenesis.
The International journal of artificial organs - 1 Sept 2009
Kiran Madanahally D, Akiyoshi Donna E, Giacometti Andrea, Cirioni Oscar, Scalise Giorgio, Balaban Naomi
Abstract excerpt
RIP is a novel antibiotic against staphylococci. It acts at least in part by competing with RNAIII activating protein (RAP) by downregulating TRAP histidine phosphorylation, and by downregulating the expression of the acessory gene regulator (agr). While much is known about the function of the agr as a quorum sensing system that regulates virulence, not much is known about TRAP. TRAP is a 167-kDa protein that is...
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