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Characterization of RAP, a quorum sensing activator of Staphylococcus aureus1

13 May 2003

Abstract excerpt

Staphylococcus aureus are Gram-positive bacteria and cause diverse serious diseases in humans and animals through the production of toxins. The production of toxins is regulated by quorum sensing mechanisms, where proteins such as RNAIII activating protein (RAP) are secreted by the bacteria and induce virulence. Antibodies to RAP have been shown to protect mice from infection, but the molecular structure of RAP...

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PMID: 12829282
DOI: 10.1016/s0378-1097(03)00326-4

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