Article
Variable epitope library-based vaccines: shooting moving targets.
Molecular immunology - 1 Dec 2009
Pedroza-Roldan Cesar, Charles-Niño Claudia, Saavedra Rafael, Govezensky Tzipe, Vaca Luis, Avaniss-Aghajani Eric, Gevorkian Goar, Manoutcharian Karen
Abstract excerpt
While the antigenic variability is the major obstacle for developing vaccines against antigenically variable pathogens (AVPs) and cancer, this issue is not addressed adequately in current vaccine efforts. We developed a novel variable epitope library (VEL)-based vaccine strategy using immunogens...
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