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Article

Antigenic variability: Obstacles on the road to vaccines against traditionally difficult targets.

Human vaccines & immunotherapeutics - 2 Oct 2016

Servín-Blanco R, Zamora-Alvarado R, Gevorkian G, Manoutcharian K

Abstract excerpt

Despite the impressive impact of vaccines on public health, the success of vaccines targeting many important pathogens and cancers has to date been limited. The burden of infectious diseases today is mainly caused by antigenically variable pathogens (AVPs), which escape immune responses induced by prior infection or vaccination through changes in molecular structures recognized by antibodies or T cells. Extensive...

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Identifiers

PMID: 27295540
DOI: 10.1080/21645515.2016.1191718
PMCID: PMC5085008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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