Article
Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI.
Obesity (Silver Spring, Md.) - 1 May 2010
Munkhtulga Lkhagvasuren, Nagashima Shuichi, Nakayama Kazuhiro, Utsumi Nanami, Yanagisawa Yoshiko, Gotoh Takaya, Omi Toshinori, Kumada Maki, Zolzaya Khadbaatar, Lkhagvasuren Tserenkhuu, Kagawa Yasuo, Fujiwara Hiroyuki, Hosoya Yoshinori, Hyodo Masanobu, Horie Hisanaga, Kojima Masayuki, Ishibashi Shun, Iwamoto Sadahiko
Abstract excerpt
Retinol-binding protein 4 (RBP4) is a recently identified adipokine that was involved in insulin resistance. RBP4 is predominantly expressed from the liver in normal metabolic state to transport retinoids throughout the body, but the exact physiological function and the regulatory mechanisms of adipocyte-derived RBP4 have not been revealed. We conducted the genetic analysis about metabolic parameters in Japanese...
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