Neonatal motor functions in Cacna1a-mutant rolling Nagoya mice.

Abstract excerpt

Rolling Nagoya mice show ataxia and carry a mutation in the Cacna1a gene, which encodes the pore-forming alpha1 subunit of the Cav2.1 channels. Because an impaired motor function has not been examined during neonatal stages in detail, we employed a battery of tests including assessments of body weight gain, righting reflex, negative geotaxis, hind-limb suspension, and tail suspension using neonatal wild-type,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aging
• Share to Animals, Newborn
• Share to Body Weight