Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autocrine and paracrine Shh signaling are necessary for tooth morphogenesis, but not tooth replacement in snakes and lizards (Squamata).

Developmental biology - 1 Jan 2010

Handrigan Gregory R, Richman Joy M

Abstract excerpt

Here we study the role of Shh signaling in tooth morphogenesis and successional tooth initiation in snakes and lizards (Squamata). By characterizing the expression of Shh pathway receptor Ptc1 in the developing dentitions of three species (Eublepharis macularius, Python regius, and Pogona vitticeps) and by performing gain- and loss-of-function experiments, we demonstrate that Shh signaling is active in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Polarity
Share to Hedgehog Proteins
Share to Lizards

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesoderm

Share to Odontogenesis

Share to Patched Receptors

Share to Snakes

Source

Identifiers

PMID: 19850027
DOI: 10.1016/j.ydbio.2009.10.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autocrine and paracrine Shh signaling are necessary for tooth morphogenesis, but not tooth replacement in snakes and lizards (Squamata).PMID 19850027Read ↗

The dynamics of supernumerary tooth development are differentially regulated by Sprouty genes.Semantic proximity Read ↗

The Shh signalling pathway in early tooth development.Semantic proximity Read ↗

Hedgehog signaling pathway: a novel model and molecular mechanisms of signal transduction.Semantic proximity Read ↗

Primary cilia regulate Shh activity in the control of molar tooth number.Semantic proximity Read ↗

Expression of SHH signaling molecules in the developing human primary dentitionSemantic proximity Read ↗

Developmental pathways of periodontal tissue regenerationSemantic proximity Read ↗

Daughters of the Enamel Organ: Development, Fate, and Function of the Stratum Intermedium, Stellate Reticulum, and Outer Enamel EpitheliumSemantic proximity Read ↗

Identification of putative dental epithelial stem cells in a lizard with life-long tooth replacementSemantic proximity Read ↗

Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid.Semantic proximity Read ↗

Differential regulation of SHH signaling and the developmental control of species-specific jaw size through neural crest-mediated Gas1 expressionSemantic proximity Read ↗

Full regeneration of the tribasal Polypterus fin.Semantic proximity Read ↗

Inhibition of SHH signaling pathway: molecular treatment strategy of odontogenic keratocyst.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.