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Identification of putative dental epithelial stem cells in a lizard with life-long tooth replacement

29 Sept 2010

Abstract excerpt

Most dentate vertebrates, including humans, replace their teeth and yet the process is poorly understood. Here, we investigate whether dental epithelial stem cells exist in a polyphyodont species, the leopard gecko (Eublepharis macularius). Since the gecko dental epithelium lacks a histologically distinct site for stem cells analogous to the mammalian hair follicle bulge, we performed a pulse-chase experiment on...

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PMID: 20876646
DOI: 10.1242/dev.052415

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