Article
High mobility group A: a novel biomarker and therapeutic target in pancreatic adenocarcinoma.
The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland - 1 Oct 2009
Liau S S, Whang E
Abstract excerpt
High mobility group A1 (HMGA1) proteins are architectural transcriptional factors that are over-expressed in a wide range of human malignancies. Recently published evidence suggests HMGA1 is a promising candidate biomarker and therapeutic target in pancreatic cancer. This review summarises data implicating HMGA1 as an important mediator of progression in human cancer and in pancreatic cancer.
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