Article
Association of XPD polymorphisms with prostate cancer in Taiwanese patients.
Anticancer research - 1 Jan 2000
Bau Da-Tian, Wu Hsi-Chin, Chiu Chang-Fang, Lin Cheng-Chieh, Hsu Chin-Moo, Wang Cheng-Li, Wang Rou-Fen, Tsai Fuu-Jen
Abstract excerpt
BACKGROUND: The DNA repair gene XPD, an important caretaker of the overall genome stability, is thought to play a major role in the development of human malignancy. Polymorphic variants of XPD, at codon 312, 751, and other sites, have been associated with cancer susceptibility, but few studies have investigated their effect on prostate cancer risk. PATIENTS AND METHODS: In this hospital-based case-control study,...
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