Article
Breast-feeding modulates the influence of the peroxisome proliferator-activated receptor-gamma (PPARG2) Pro12Ala polymorphism on adiposity in adolescents: The Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) cross-sectional study.
Diabetes care - 1 Jan 2010
Verier Caroline, Meirhaeghe Aline, Bokor Szilvia, Breidenassel Christina, Manios Yannis, Molnár Dénes, Artero Enrique G, Nova Esther, De Henauw Stefaan, Moreno Luis A, Amouyel Philippe, Labayen Idoia, Bevilacqua Noemi, Turck Dominique, Béghin Laurent, Dallongeville Jean, Gottrand Frédéric
Abstract excerpt
OBJECTIVE: The peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala polymorphism has been associated with a higher BMI and a lower risk of type 2 diabetes in adulthood. The association between adiposity and PPARG variants can be influenced by environmental factors such as early growth, dietary fat, and (as recently shown) breast-feeding. The objectives of this study were to assess 1) the influence...
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