Article
Genetic variation in pentraxin (PTX) 3 gene associates with PTX3 production and fertility in women.
Biology of reproduction - 1 Feb 2010
May Linda, Kuningas Maris, van Bodegom David, Meij Hans J, Frolich Marijke, Slagboom P Eline, Mantovani Alberto, Westendorp Rudi G J
Abstract excerpt
Pentraxin 3 (PTX3) plays an important role in innate immune responses and in female fertility, as discovered with studies in mice. However, the role of PTX3 in human fertility is unknown. Here, we report on a population-based study from a rural area of Upper East Ghana (n = 4346). We studied the association between the number of children given birth by women during their lifetime and ex vivo, lipopolysaccharide...
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