Interleukin-8 and -10 gene polymorphisms in irritable bowel syndrome.

doi:10.1007/s11033-012-1745-2

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Article

Interleukin-8 and -10 gene polymorphisms in irritable bowel syndrome.

Molecular biology reports - 1 Sept 2012

Romero-Valdovinos Mirza, Gudiño-Ramírez Areli, Reyes-Gordillo Jesús, Martínez-Flores Williams Arony, Ramírez-Miranda María Elena, Maravilla Pablo, Olivo-Díaz Angélica

Abstract excerpt

Irritable bowel syndrome (IBS) is one of the most common gastrointestinal diagnoses seen by primary care providers and gastroenterologists. Proinflammatory cytokines interleukin (IL)-6 and IL-8 have been found increased in IBS patients. Cytokine gene single nucleotide polymorphisms (SNPs) of IL-8 and IL-10 have not been assessed in Mexican IBS patients. DNA was extracted from peripheral blood leucocytes of 45 IBS...

Topics

Adult
Alleles
Case-Control Studies
Female
Gene Frequency
Genotype
Humans
Interleukin-10
Interleukin-8
Irritable Bowel Syndrome
Male
Middle Aged
Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 22740130
DOI: 10.1007/s11033-012-1745-2

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