Article
Association of interleukin-8 gene polymorphisms and haplotypes with oral lichen planus in a Chinese population.
Inflammation - 1 Apr 2010
Dan Hongxia, Liu Wenzhao, Zhou Yu, Wang Jiayi, Chen Qianming, Zeng Xin
Abstract excerpt
Interleukin-8 (IL-8), a CXC chemokine with multiple biological functions, plays an important role in the pathogenesis of oral lichen planus (OLP). The aim of this study was to investigate the association of single nucleotide polymorphisms (SNPs) of IL-8 gene with OLP in a Chinese population. Four SNPs of the IL-8 gene at positions -845 T/C (rs2227532), -738 T/A, -251 A/T (rs4073) and +781 C/T (rs2227306) were...
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