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Article

Association of interleukin-8 polymorphism (+ 781 C/T) with the risk of oral Lichen Planus disease.

BMC oral health - 20 Jun 2023

Ghasemi Haniyeh, Mozaffari Hamid Reza, Kohsari Maryam, Hatami Masoud, Yari Kheirollah, Marabi Mohammad Hesam

Abstract excerpt

BACKGROUND: Oral Lichen Planus (OLP) is a chronic inflammatory mucosal disease. The pathogenesis of OLP is unknown. The Single Nucleotide Polymorphism (SNP) that occurs in the regulatory position + 781 could affect the expression of interleukin-8. This polymorphism is probably associated with increased serum levels of IL-8. The current study aimed to investigate the genotype and allele frequencies of...

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PMID: 37340381
DOI: 10.1186/s12903-023-03088-7
PMCID: PMC10280860

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