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Article

Thymus microenvironment in human primary immunodeficiency diseases.

Current opinion in allergy and clinical immunology - 1 Dec 2009

Poliani Pietro Luigi, Vermi William, Facchetti Fabio

Abstract excerpt

PURPOSE OF REVIEW: Severe combined immunodeficiencies represent a heterogeneous group of genetic disorders affecting genes of both early and late steps in lymphocytes development, a process tightly controlled by thymic epithelial cells. Detailed analysis of thymic morphology aids to the assessment of the severity of the immune disorder and may be critical to the understanding of the role of the genetic defects in...

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Identifiers

PMID: 19841578
DOI: 10.1097/ACI.0b013e3283327e5c

Genes

AIRE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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