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Localization and Developmental Regulation of a Dispersed Gene Family 1 Protein in Trypanosoma cruzi

20 Oct 2009

Abstract excerpt

The dispersed gene family 1 (DGF-1) is the fifth largest gene family in the Trypanosoma cruzi genome, with over 500 members (11). Many of the predicted DGF-1 protein products have several transmembrane domains and N-glycosylation and phosphorylation sites and were thought to localize in the plasma membrane. Here, we report that affinity-purified antibodies against a region of one of these proteins (DGF-1.2)...

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PMID: 19841080
DOI: 10.1128/iai.00780-09

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