Article
Two novel SNPs in HSF1 gene are associated with thermal tolerance traits in Chinese Holstein cattle.
DNA and cell biology - 1 Apr 2011
Li Qiu-Ling, Ju Zhi-Hua, Huang Jin-Ming, Li Jian-Bin, Li Rong-Ling, Hou Ming-Hai, Wang Chang-Fa, Zhong Ji-Feng
Abstract excerpt
Heat-shock transcription factors (HSFs) play an important role in regulating heat stress response. The activation of heat-shock protein (HSP) genes is mediated by HSFs, which bind to promoters of HSP genes. In this research, two novel single nucleotide polymorphisms, T909C and G4693T, and their association with thermal tolerance were investigated in 951 Chinese Holstein cattle. Linkage disequilibrium and...
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