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Novel SNPs in HSP70A1A gene and the association of polymorphisms with thermo tolerance traits and tissue specific expression in Chinese Holstein cattle.

Molecular biology reports - 1 Apr 2011

Li Qiuling, Han Jianbo, Du Fanglei, Ju Zhihua, Huang Jinming, Wang Ji, Li Rongling, Wang Changfa, Zhong Jifeng

Abstract excerpt

Heat stress induces heat shock proteins (HSPs) expression and HSP70 family is one of them that have been reported to involve in cellular protection against heat stress. But whether there is any association of genetic variation in the HSP70A1A gene with thermo tolerance is unknown. PCR-SSCP and DNA sequencing were used to detect possible SNPs in HSP70A1A gene in 890 Chinese Holstein cattle. Three fragments were...

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PMID: 21082257
DOI: 10.1007/s11033-010-0407-5

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