Article
Serum heat shock protein 70 level as a biomarker of exceptional longevity.
Mechanisms of ageing and development - 1 Nov 2006
Terry Dellara F, Wyszynski Diego F, Nolan Vikki G, Atzmon Gil, Schoenhofen Emily A, Pennington JaeMi Y, Andersen Stacy L, Wilcox Marsha A, Farrer Lindsay A, Barzilai Nir, Baldwin Clinton T, Asea Alexzander
Abstract excerpt
Heat shock proteins are highly conserved proteins that, when produced intracellularly, protect stress exposed cells. In contrast, extracellular heat shock protein 70 (Hsp70) has been shown to have both protective and deleterious effects. In this study, we assessed heat shock protein 70 for its potential role in human longevity. Because of the importance of HSP to disease processes, cellular protection, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.