Article
Vessel formation is induced prior to the appearance of cartilage in BMP-2-mediated heterotopic ossification
20 Oct 2009
Abstract excerpt
Heterotopic ossification (HO), or endochondral bone formation at nonskeletal sites, often results from traumatic injury and can lead to devastating consequences. Alternatively, the ability to harness this phenomenon would greatly enhance current orthopedic tools for treating segmental bone defects. Thus, understanding the earliest events in this process potentially would allow us to design more targeted therapies...
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