Genetic polymorphism of VEGF-1154 (A/G) in laryngeal squamous cell carcinoma.

doi:10.1016/j.arcmed.2007.09.008

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Article

Genetic polymorphism of VEGF-1154 (A/G) in laryngeal squamous cell carcinoma.

Archives of medical research - 1 Feb 2008

Unal Zeynep Nil, Unal Murat, Bağdatoğlu Ozlen Tubay, Polat Gürbüz, Atik Uğur

Abstract excerpt

BACKGROUND: Angiogenesis has been shown to be increased in various human tumors including head and neck squamous cell carcinoma (SCC). Vascular endothelial growth factor (VEGF) is thought to be one of the most important angiogenic factors in tumorigenesis. In this study, we aimed to investigate whether polymorphism of VEGF-1154 (A/G) genotypes are associated with the risk of laryngeal SCC. METHODS: A prospective,...

Topics

Adult
Aged
Biomarkers, Tumor
Case-Control Studies
Female
Follow-Up Studies
Genotype
Head and Neck Neoplasms
Humans
Laryngeal Neoplasms
Male
Middle Aged
Neovascularization, Pathologic
Polymorphism, Single Nucleotide
Prospective Studies
Risk Factors
Vascular Endothelial Growth Factor A
White People

Source

Open in PubMed

Identifiers

PMID: 18164965
DOI: 10.1016/j.arcmed.2007.09.008

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