Lack of association of the alpha-1-antitrypsin PIZ allele with rheumatoid arthritis or with its extra articular complications.

Article

Lack of association of the alpha-1-antitrypsin PIZ allele with rheumatoid arthritis or with its extra articular complications.

Disease markers - 1 Jan 2000

Steers G, McMahon M J, Grennan D M, Hillarby M C

Abstract excerpt

PIZ allele frequencies were defined by PCR amplification and hybridization using a PIZ SSO (sequence specific oligonucleotide) probe. The groups studied included 64 normal controls, 104 subjects with rheumatoid arthritis (RA) without any extra-articular features, 29 of whom had severe arthritis a...

Topics

Alleles
Arthritis, Rheumatoid
Base Sequence
Bronchiectasis
Genetic Markers
HLA-DR4 Antigen
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Pulmonary Fibrosis
alpha 1-Antitrypsin

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