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Article

DC-SIGN as a receptor for phleboviruses.

Cell host & microbe - 21 Jul 2011

Lozach Pierre-Yves, Kühbacher Andreas, Meier Roger, Mancini Roberta, Bitto David, Bouloy Michèle, Helenius Ari

Abstract excerpt

During natural transmission, bunyaviruses are introduced into the skin through arthropod bites, and dermal dendritic cells (DCs) are the first to encounter incoming viruses. DC-SIGN is a C-type lectin highly expressed on the surface of dermal DCs. We found that several arthropod-borne phleboviruses (Bunyaviridae), including Rift Valley fever and Uukuniemi viruses, exploit DC-SIGN to infect DCs and other...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21767814
DOI: 10.1016/j.chom.2011.06.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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