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Article

Overexpression of Prostate-Specific <i>TMPRSS2(exon 0)-ERG</i> Fusion Transcripts Corresponds with Favorable Prognosis of Prostate Cancer

14 Oct 2009

Abstract excerpt

PURPOSE: To gain insight in the mechanism and clinical relevance of TMPRSS2-ERG expression in prostate cancer, we determined the specific characteristics of fusion transcripts starting at TMPRSS2 exon 1 and at a more upstream and less characterized exon 0. EXPERIMENTAL DESIGN: We used quantitative PCR analysis to investigate expression of wild-type TMPRSS2(exon 0) and TMPRSS2(exon 1) and of ERG fusion...

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PMID: 19825963
DOI: 10.1158/1078-0432.ccr-09-1176

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